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The deadly threat of gene drives

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The UN Biodiversity Conference began on 13 November 2018 in Sharm El-Sheikh, Egypt, and until its close on 29 November will call on decision makers from more than 190 countries to step up efforts to “halt biodiversity loss and protect the ecosystems that support food and water security and health for billions of people”.

On 17 November, the Conference of Parties to the Cartagena Protocol of the UN Convention on Biological Diversity begins. On the agenda is a vital subject that has been moved to the centre of the meeting’s deliberations: a technology called ‘gene drives’. This part of the UN Biodiversity Conference will discuss several key draft decisions about the risks it poses and how to deal with them, including through a moratorium on the technology.

What are ‘gene drives’? Gene drive organisms are supposed to ‘force’ one or more genetic traits onto future generations of their own species. The term for gene drives used by French scientists, ‘Forçage Génétique’ (genetic forcer) makes the intention clear: to force an engineered genetic change through an entire population or even an entire species. If permitted, such organisms could accelerate the distribution of corporate-engineered genes from the lab to the rest of the living world at dizzying speed and in an irreversible process.

As a must-read explainer of this menacing new technology, prepared by the ETC Group and the Heinrich Böll Stiftung, has put it, such organisms “are designed, over time, to replace non-gene drive organisms of the same species in a population via an uncontrolled chain reaction – this ability may make them a far more dangerous biohazard than genetically modified organisms (GMOs)”. [The report, released in October 2018, is ‘Forcing The Farm: How Gene Drive Organisms Could Entrench Industrial Agriculture and Threaten Food Sovereignty’.]

Recently, a study by the Bundesamt für Naturschutz, which is the central scientific authority of the German federal government for both national and international nature conservation, warned that “with gene drives, GMO applications are moving directly from crop plants to modifying wild species. Major consequences on semi-natural and natural ecosystems are expected.” The research concludes that “a clear understanding
and analysis of these differences is crucial for any risk assessment regime and a socially acceptable and
ethical evaluation that is vital for the application of [GDO] technology”.

More pertinent to the current model of the transnational cartelisation of industrial agricultre, a group of French researchers recently concluded: “The time frame of gene drive perfectly fits the economic development strategies dominant today in agribusiness, with a focus on short-term return on investments and disdain for long-term issues. The current economic system based on productivity, yields, monoculture, and extractivism is a perfect match for the operating mode of gene drive.” [From ‘Agricultural pest control with CRISPR‐based gene drive: time for public debate’ by Virginie Courtier‐Orgogozo, Baptiste Morizot and Christophe Boëte in EMBO Reports.]

Reading these warnings helps form better clarity about what GDOs are and are not. From what I have been able to understand, normal reproductive biology gives the offspring of sexually reproducing organisms a 50:50 chance of inheriting a gene from their parents. The gene drives however is an invasive technology to ensure that within a few generations, all that organisms offspring will contain an engineered gene!

Why the phase shift from the already dangerous GMO to the threatening of an entire species by GDO? Thanks to rising consumer awareness of the dangers of GMO food crops, vegetables and fruit – which is now visible even in India (a generation-and-a-half later than Europe) where the central and state governments have put not a rupee into educating consumers about pesticide and synthetic fertiliser poisoning, let alone GMOs) – the uptake of GMOs is levelling off as the predicted risks have become evident, such as the intensification of the treadmill of increased use of toxic chemicals. The so-called ‘gene editing’ techniques, and particularly GDOs, has given the industrial agriculture-biotech-seed multinational corporations a strategy to regain the pace of their domination of food cultivation and therefore food control.

Recognising the extreme danger, the UN Biodiversity Conference which is now under way in Egypt, and particularly the part of the conference beginning on 17 November which is the Conference of Parties to the Cartagena Protocol of the Convention on Biological Diversity (CBD), have placed gene drives on the agenda. [The Cartagena Protocol on Biosafety to the Convention on Biological Diversity is an international agreement which aims to ensure the safe handling, transport and use of living modified organisms (LMOs) resulting from modern biotechnology that may have adverse effects on biological diversity, taking also into account risks to human health. It was adopted on 29 January 2000 and entered into force on 11 September 2003.]

The meeting will discuss, under ‘Risk assessment and risk management’ (which are Articles 15 and 16 of the Protocol) draft decisions on gene drives and, we must hope, take them while imposing a moratorium on this evil technology. [Draft decision document CBD/CP/MOP/9/1/ADD2]. The draft decisions are:

3. Also recognises that, as there could be potential adverse effects arising from organisms containing engineered gene drives, before these organisms are considered for release into the environment, research and analysis are needed, and specific guidance may be useful, to support case-by-case risk assessment;

4.Notes the conclusions of the Ad Hoc Technical Expert Group on Synthetic Biology that, given the current uncertainties regarding engineered gene drives, the free, prior and informed consent of indigenous peoples and local communities might be warranted when considering the possible release of organisms containing engineered gene drives that may impact their traditional knowledge, innovation, practices, livelihood and use of land and water;

5. Calls for broad international cooperation, knowledge sharing and capacity-building to support, inter alia, Parties in assessing the potential adverse effects on the conservation and sustainable use of biodiversity from [living modified organisms produced through genome editing,] living modified organisms containing engineered gene drives and living modified fish, taking into account risks to human health, the value of biodiversity to indigenous peoples and local communities, and relevant experiences of individual countries in performing risk assessment of such organisms in accordance with annex III of the Cartagena Protocol;

The concerns of the CBD and the warnings of scientists have been entirely ignored by the agricultural biotechnology corporations and by the inter-connected funding organisations and research groups engaged in synthetic biology. As the report, ‘Forcing The Farm’, has said, multimillion-dollar grants for gene drive development have been given by Gates Foundation, the Foundation for the National Institutes of Health, the Open Philanthropy Institute, the Wellcome Trust and the US Defense Advanced Research Projects Agency. These include generous allowances for what is called ‘public message testing’ and ‘public engagement exercises’ – making GDOs sound beneficial to society and glossing over the dangers – and lobbying of governments and policy-makers.

What is particularly worrying for us in India is the role of the Tata Trusts in financing research on GDOs. In 2016 October an American university, the University of California San Diego, received a US$70 million commitment from the Tata Trusts (which now is the umbrella organisation for what earlier were the Sir Dorabji Tata Trust, the Sir Ratan Tata Trust and the Tata Education and Development Trust, and in terms of funding capacity is probably the largest in India) to establish the Tata Institute for Active Genetics and Society (TIAGS).

This new institute is described as a collaborative partnership between the university and research operations in India. A university press release had said: “UC San Diego, which will be home to the lead unit of the institute (TIAGS-UC San Diego), will receive US$35 million in funding, while the remainder of the committed funds is anticipated to support a complementary research enterprise in India (TIAGS-India).”

India is a signatory to the Cartagena Protocol of the Convention on Biological Diversity (signed 23/01/2001, ratified 17/01/2003, entered into force 11/09/2003) and its reporting to the Protocol on risk assessments of GMOs (which have officially not been used on food crops) has been worse than desultory – the five risk assessments submitted by India are all in 2012 for Bt cotton hybrids.

The shameful co-option of the statutory Genetic Engineering Approval Committee by India’s biotech companies, which was fully revealed in 2016 during the furore over the Committee’s bid to have GM mustard approved, has shown that the entire biosafety assessment process in India and its ability to actually protect our environment and citizens’ health from the profoundly menacing risks of biotechnology, is compromised.

The Gates Foundation, which has graduated from influencing central and state government policy in health and agriculture to becoming an implementing agency, and which has invested heavily in synthetic biotechnology and GDOs (such as ‘Target Malaria’, which uses gene drives against mosquitoes) is now collaborating with the Tata Trusts in health, nutrition and crop cultivation together with the American aid agency USaid and other foundations that claim philanthropic intentions. The risks to our agro-ecological methods, our local crop cultivation knowledge, our food and our public healthcare system have now become far more threatening.

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GM and its public sector servants in India

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[Continued from part one.]

The facade of sophisticated science carries with it an appeal to the technocrats within our central government and major ministries, and to those in industry circles, with the apparently boundless production and yield vistas of biotechnology seeming to complement our successes in space applications, in information technology, in nuclear power and complementing the vision of GDP growth.

Framed by such science, the messages delivered by the biotech MNC negotiators and their compradors in local industry appear to be able to help us fulfil the most pressing national agendas: ensure that food production keeps pace with the needs of a growing and more demanding population, provide more crop per drop, deliver substantially higher yield per acre, certified and high-performing seeds will give farmers twice their income, consumers will benefit from standardised produce at low rates, crops will perform even in more arid conditions, the use of inputs will decrease, and the litany of promised marvels goes on.

Yet it is an all-round ignorance that has allowed such messages to take root and allowed their messengers to thrive in a country that has, in its National Gene Bank over 157,000 accessions of cereals (including 95,000 of paddy and 40,000 of wheat), over 56,000 accessions of millets (the true pearls of our semi-arid zones), over 58,000 accessions (an accession is a location-specific variety of a crop species) of pulses, over 57,000 of oilseeds (more than 10,000 of mustard), and over 25,000 of vegetables.

And even so the National Bureau of Plant Genetic Resources reminds us that while the number of cultivated plant species is “relatively small and seemingly insignificant”, nature in India has evolved an extraordinary genetic diversity in crop plants and their wild relatives which is responsible for every agro-ecological sub-region, and every climatic variation and soil type that may be found in such a sub-region, being well supplied with food.

With such a cornucopia, every single ‘framed by great science’ claim about a GM crop made by the biotech MNCs must fall immediately flat because we possess the crop diversity that can already deliver it. Without the crippling monopolies that underlie the science claim, for these monopolies and licensing traps are what not only drove desi cotton out when Bt cotton was introduced but it did so while destroying farming households.

Without the deadly risk of risk of genetic contamination and genetic pollution of a native crop (such as, GM mustard’s risk to the many varieties of native ‘sarson’). Without the flooding of soil with a poison, glufosinate, that is the herbicide Bayer-Monsanto will force the sale of together with its GM seed (‘Basta’ is Bayer’s herbicide that is analogous to Monsanto’s fatal Glyphosate, which is carcinogenic to humans and destroys other plant life – our farmers routinely intercrop up to three crop species, for example mustard with chana and wheat, as doing so stabilises income).

Whereas the veil of ignorance is slowly lifting, the immediate questions that should be asked by food grower and consumer alike – how safe is it for plants, soil, humans, animals, pollinating insects and birds? what are the intended consequences? what unintended consequences are being studied? – are still uncommon when the subject is crop and food. This is what has formed an ethical and social vacuum around food, which has been cunningly exploited by the biotech MNCs and indeed which India’s retail, processed and packaged foods industry have profited from too.

When in October 2016 our National Academy of Agricultural Sciences shamefully and brazenly assured the Ministry of Environment, Forests and Climate Change on the safety of GM mustard, it did so specifically “To allay the general public concerns”. What followed was outright lies, such as “herbicide is used in the process only in hybrid production plot”, “The normal activity of bees is not affected”, “GE Mustard provides yield advantage”, “no adverse effect on environment or human and animal health”. None of these statements was based on study.

India grows food enough to feed its population ten years hence. What affects such security – crop choices made at the level of a tehsil and balancing the demands on land in our 60 agro-ecological sub-zones and 94 river sub-basins – is still influenced by political position, the grip of the agricultural ‘inputs’ industry on farmers, economic pressures at the household level, and the seasonal cycle. In dealing with these influences, ethics, safety and social considerations are rarely if ever in the foreground. Yet India is a signatory to the UN Convention on Biological Diversity and its Cartagena Protocol on Biosafety, whose Article 17 requires countries to prevent or minimise the risks of unintentional transboundary movements of genetically engineered organisms.

Neither the Genetic Engineering Approval Committee (GEAC), in the case of GM mustard, nor the Department of Biotechnology, the Department of Science and Technology (whose Technology Information, Forecasting and Assessment Council in a 2016 report saw great promise in genetic engineering for India), the Ministries of Environment and Agriculture, the Indian Council of Agricultural Research (ICAR, with its 64 specialised institutions, 15 national research centres, 13 directorates, six national bureaux and four deemed universities), the Council for Scientific and Industrial Research (CSIR) have mentioned ethics, consumer and environment safety, or social considerations when cheering GM.

This group of agencies and institutions which too often takes its cue from the west, particularly the USA (which has since the 1950s dangled visiting professorships and research partnerships before the dazzled eyes of our scientific community) may find it instructive to note that caution is expressed even by the proponents of genetic engineering technologies in the country that so inspires them. In 2016 a report on ‘Past Experience and Future Prospects’ by the Committee on Genetically Engineered Crops, National Academies of Sciences, Engineering, and Medicine of the USA, recognised that the public is sceptical about GE crops “because of concerns that many experiments and results have been conducted or influenced by the industries that are profiting from these crops” and recommended that “ultimately, however, decisions about how to govern new crops need to be made by societies”.

Practices and regulations need to be informed by accurate scientific information, but recent history makes clear that what is held up as unassailable ‘science’ is unfortunately rarely untainted by interests for whom neither environment nor human health matter.

[This is the second part of an article that was published by Swadeshi Patrika, the monthly journal of the Swadeshi Jagran Manch. Part one is here.]

Desperate food gambits and the danger to India

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India’s Republic Day in 2015 will also see the visit of the president of the USA, Barack Obama, accompanied by the usual large delegation of business persons, lobbyists and functionaries of the American government. They will use this visit to demand many things, and amongst the demands will be that the NDA-BJP government ‘reform’ all that is hindering the agriculture and food transformation in Bharat.

A couple tending their stack of rice stalks residue in the Konkan.

A couple tending their stack of rice stalks residue in the Konkan.

We must resist this with strength and perseverance. So far, the NDA-BJP government has not shown that it recognises or understands the threats and dangers, which are very very serious indeed. The American delegation will push this government to clear the way for genetically modified seed and crop (including in food staples such as cereals), for the further industrialisation and mechanisation of crop production (which will mean the removal of smallholder ‘kisans’ from their plots, all in the name of market efficiency), and the deepening of the food processing and food retail industries’ grip on what we eat.

The Prime Minister’s Office, the Union Cabinet and the seniormost bureaucrats of the major ministries involved must wake up to this threat and be firm against it. The signals from elsewhere are many and they are clear about what lies in store for Bharat if the NDA-BJP government at the centre and if state governments do not discharge their duty – which is, safeguard the sovereignty of Bharat.

Already in Europe, the German Environment Ministry is insisting on a complete ban on green genetic engineering in Germany. Under a new European Parliament directive, member states of the European Union will now be able to restrict or completely ban GMO cultivation within their borders. One of the leading proponents of such a legal ban in Germany is its Ministry of Agriculture, which also supports a national ban on cultivation.

soilatlas2015_main_1Moreover, in a position paper from the Federal Ministry of the Environment, Minister Barbara Hendricks said she does not want to leave any back doors open for genetic engineering. The GMO law must be changed, so that controversial green genetic engineering cannot be used under any pretext in Germany, she stated in the document. “Green genetic engineering has turned out to be the wrong track,” Hendricks said. “It is risky for nature and the environment and is not desired by consumers.”

Worldwide, the project to fully industrialise global food production is far from complete, yet already it is responsible for most deforestation, most marine pollution, most coral reef destruction, much of greenhouse gas emissions, most habitat loss, most of the degradation of streams and rivers, most food insecurity, most immigration, most water depletion, and massive human health problems.

Relationships between soil, urbanisation, fertiliser use, farming, ecology and health. Images from the Soil Atlas, 2015, Heinrich Böll Stiftung.

Relationships between soil, urbanisation, fertiliser use, farming, ecology and health. Images from the Soil Atlas, 2015, Heinrich Böll Stiftung.

Under GM- and tech-centric industrial agriculture and food systems – which is what the Americans will demand from us – countries are becoming literally uninhabitable as a result of the social and ecological consequences.

Wherever industrial and genetically engineered agriculture is found, landscapes are left progressively emptier of life. Eventually, the soil turns either into mud that washes into the rivers or into dust that blows away on the wind. Industrial agriculture has no long term future and is ecological suicide. But those who profit from it cannot allow all this to become broadly understood – and unfortunately that has included our NDA-BJP government. That is why they have continued to peddle the lie of food scarcity in India, which the previous Congress government employed so recklessly.

The agriculture and food problem – which will become a more extreme problem for us if the Obama group is given its way – is closely interlinked with growing demand for land. Land is a lucrative investment and has fuelled the real estate boom in India for the last decade. But for our smallholder kisans it is the source of livelihood, as it is for our shepherd groups and tribal communities. Rising demand for land also harms the ecosystem – as is seen in each and every one of the 63 cities whose populations this year are at least one million. The more intensive the farming, the more damage it does to the environment. This is the main reason for the decline in biological diversity, above and below the ground.

The American push will be for agri-food systems in accordance with the new international trade agreements. These are nothing but colonial ways of thinking – that food should be produced for international export as a tool of foreign policy and to control populations (especially through GM) and as a byproduct financially benefit powerful corporations that act as agents of such colonial ways of thinking. Thus it is a direct assault on people’s sovereignty over their natural resources, farming systems and food access as well as their human right to dignified living standards free of exploitation and dependence.

Such treaties (such as the TTP which is facing opposition even amongst those the USA calls allies) are dangerous because they are negotiated in secret. But what has emerged (thanks to leaks) is appalling. Some of the texts in these treaties wants the outright patenting of plants and animals, many draft agreements come with severe punishments for farmers who break intellectual property laws, they deliberately undermine local agriculture (as seen with NAFTA), commons lands are proposed for privatisation, labelling of GM foods will be prohibited, and the governments of countries that try to undo the damage will be liable to be sued by the multi-national corporations. This is the extent of the danger facing Bharat, which will become more clear come Republic Day 2015.

Scientists’ statement deflates the bogus idea of ‘safe’ GM

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ENSSER_GMO_statement_10More scientists, physicians and legal experts have signed the group statement issued by the European Network of Scientists for Social and Environmental Responsibility (ENSSER) on the safety of genetically modified organisms (GMOs). The number of initial signatories to the statement, titled ‘No scientific consensus on GMO safety’, was almost 100 on the day it was released, 2013 October 21, and has more than doubled since.

The ENSSER group has reminded us that crop genetic engineering is dominated not by ecological experts but by molecular biologists: “Many are not knowledgeable about ecological risks and – more importantly – they fail to recognise the limitations of their expertise.”

ENSSER_GMO_statement_13Regarding the environmental risk of GM crops, ENSSER has said, the negative effects now documented empirically have been predicted since about 25 years.

For instance, while naturally occurring Bt toxins come in a diversity of variants, GM crops necessarily have to choose one Bt toxin to be transferred, significantly enhancing the probability of resistance development. Such effects are analysed by community ecology researchers and not visible on the genetic level.

“So it is a shame that, more than 20 years after the international academic societies of ecologists and molecular biologists agreed on the complementarity of their competences, and the necessity to assess ecosystem impacts in a systemic fashion, today’s molecular biologists still do neither recognise nor respect the limits of their competencies (not to speak about the influence of funding). Ignoring one’s own blind spots is what can turn science into a social risk.”

ENSSER_GMO_statement_11Those who have signed the statement “strongly reject claims by GM seed developers and some scientists, commentators, and journalists that there is a ‘scientific consensus’ on GMO safety and that the debate on this topic is ‘over’.”

The signatories have said they “feel compelled to issue this statement because the claimed consensus on GMO safety does not exist. The claim that it does exist is misleading and misrepresents the currently available scientific evidence and the broad diversity of opinion among scientists on this issue. Moreover, the claim encourages a climate of complacency that could lead to a lack of regulatory and scientific rigour and appropriate caution, potentially endangering the health of humans, animals, and the environment”.

ENSSER_GMO_statement_16ENSSER members and non-members alike who have signed the statement have collectively said that science and society do not proceed on the basis of a constructed consensus, as current knowledge is always open to well-founded challenge and disagreement. They endorse the need for further independent scientific inquiry and informed public discussion on GM product safety and urge GM proponents to do the same.

Regarding the safety of GM crops and foods for human and animal health, a comprehensive review of animal feeding studies of GM crops found that most studies concluding that GM foods were as safe and nutritious as those obtained by conventional breeding were “performed by biotechnology companies or associates, which are also responsible [for] commercialising these GM plants”.

ENSSER_GMO_statement_12It is often claimed that “trillions of GM meals” have been eaten in the US with no ill effects. However, no epidemiological studies in human populations have been carried out to establish whether there are any health effects associated with GM food consumption. As GM foods are not labelled in North America, a major producer and consumer of GM crops, it is scientifically impossible to trace, let alone study, patterns of consumption and their impacts. Therefore, claims that GM foods are safe for human health based on the experience of North American populations have no scientific basis.

ENSSER_GMO_statement_15A report by the British Medical Association concluded that with regard to the long-term effects of GM foods on human health and the environment, “many unanswered questions remain” and that “safety concerns cannot, as yet, be dismissed completely on the basis of information currently available”. The report called for more research, especially on potential impacts on human health and the environment.

ENSSER_GMO_statement_14Likewise, a statement by the American Medical Association’s Council on Science and Public Health acknowledged “a small potential for adverse events … due mainly to horizontal gene transfer, allergenicity, and toxicity” and recommended that the current voluntary notification procedure practised in the US prior to market release of GM crops be made mandatory. The ENSSER group has said that even a “small potential for adverse events” may turn out to be significant, given the widespread exposure of human and animal populations to GM crops.

India marches against Monsanto, hauls it back into court

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The anti-GM and anti-Monsanto protest in Bangalore outside the Town Hall on 2013 October 15

The anti-GM and anti-Monsanto protest in Bangalore outside the Town Hall on 2013 October 15

This is an important week for the public movement in India against genetically-modified seed and food, and against the corporate control of agriculture. Just ahead of World Food Day 2013, the Coalition for GM Free India has held public protests, marches and events in major cities – Bangalore, Mumbai, New Delhi, Thiruvananthapuram and Chennai.

“Today, India is also under threat from the hazardous products that Monsanto wants to profiteer from – these are products that affect the very food that we eat to survive and stay healthy and our environment. These are products that have the potential to jeopardise future generations too,” said the Coalition at the protest meetings and marches.

These actions have come when, in a very significant ruling by the High Court of Karnataka, a petition to dispose criminal prosecution of the Monsanto subsidiary in India, representatives of an agricultural university and a partner company, has been dismissed.

RG-Monsanto_BLR_protest_10Mahyco-Monsanto, the Indian seed company, the University of Agricultural Sciences Dharwad (which is in the state of Karnataka), and Monsanto collaborating partners Sathguru Consultants were accused by the National Biodiversity Authority and the Karnataka State Biodiversity Board of committing serious criminal acts of biopiracy in promoting B.t. Brinjal, India’s first food GMO.

The Bangalore-based Environment Support Group (ESG) had said to the court that the entire process by which the product had been developed violated the Biological Diversity Act, 2002, and the Convention on Biological Diversity, 1992, and “constituted an outrageous act of biopiracy of India’s endemic brinjal (eggplant) varieties”.

To substantiate this charge, the ESG produced evidence that all the endemic varieties of brinjal that had been accessed by the University of Agricultural Sciences Dharwad and Monsanto-Mahyco, with technical support from Sathguru Consultants and USAID, and the act of inserting the B.t. gene (a proprietary product of Monsanto), were undertaken without any consent of local Biodiversity Management Committees, the State Biodiversity Board and the National Biodiversity Authority.

As the Coalition for GM Free India has pointed out repeatedly, Monsanto’s misdeeds in India and its growing threat to food security and the right to food cultivation and consumption choices are considerable:
* Mahyco-Monsanto used its Bt cotton seed monopoly to set exorbitant prices. The Andhra Pradesh government had to use the MRTP (Monopolies and Restrictive Trade Practices) Commission, which observed that Monsanto-Mahyco was using unfair trade practices in India, while asking the company to reduce the royalty/sub-licensing fee being charged in India.
* Monsanto-Mahyco did not hesitate to sue governments in India on issues related to compensation for loss-incurring farmers or price-regulation.
* After the advent of Bt cotton, Monsanto entered into licensing agreements with most seed companies in India so that out of 22.5 million acres of GM cotton, 21 million acres is planted with its seed, Bollgard. Today it controls nearly 93% of the market share of cotton seeds in India, with little choice left to farmers.
* Monsanto is on the Board of the Indo-US Knowledge Initiative in Agriculture, under which bio-safety regime for GM crops was sought to be weakened.
* Monsanto entered into agreements with several states (Rajasthan, Orissa, Gujarat, Himachal Pradesh, Jammu and Kashmir) under which the states spend hundreds of crore rupees of public funds every year to purchase hybrid maize seeds from them. Such agreements were found to have no scientific or funding rationale to support them. Appraisals have shown these to be risky for farmers. However, the corporation has found huge, ready markets supported by taxpayers’ funds!
* Monsanto is pushing the sales of its herbicide glyphosate which is known to cause reproductive problems. Approval for its herbicide-tolerant GM crops would skyrocket the use of this hazardous chemical in our fields.

The action in court and on the streets of major cities must be recognised by the central and state governments in order to pursue the criminal prosecution against biopiracy in B.t. brinjal. This is critical, said the ESG, because it is for the “first time that India has sought to implement the provisions of the Biodiversity Act tackling biopiracy, and thus the effort constitutes a major precedent to secure India’s bio-resources, associated traditional knowledge and biodiversity for the benefit of present and future generations”.

Formation of the ‘Big 6’ seed-biotech-crop companies

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Over the past 15 years, the world seed industry has consolidated through mergers and acquisitions. This graphic, extracted from a 2011 December USDA report, shows how the ‘Big 6’ got to the positions they now occupy (I have added colour to make it easier to distinguish each dominant conglomerate’s consolidation history).

Formation of the 'Big 6' seed-biotech-crop companies. Graphic from: Research Investments and Market Structure in the Food Processing, Agricultural Input, and Biofuel Industries Worldwide / ERR-130. Economic Research Service / U.S. Department of Agriculture (USDA) (Report Number 130, December 2011) (click for the full size png image, 652kb).

Over the past 15 years, the world seed industry has consolidated through mergers and acquisitions. This graphic, extracted from a 2011 December USDA report, shows how the ‘Big 6’ got to the positions they now occupy (I have added colour to make it easier to distinguish each dominant conglomerate’s consolidation history).

An excerpt from the USDA report has explained some of the features of changes to the seed industry which can be summarised as follows:

1. Among the largest firms in terms of total product sales, the close relationships between seed and agricultural chemicals industries have continued. This applies to the Big 6 firms in particular. These relationships may result partially from complementarity of product lines such as herbicide-tolerant seeds and chemical herbicides, or possibly from economies of scope in marketing as well. Chemical companies also realized GM crops with pest resistance traits would compete with the crop protection chemicals, which helped drive these companies’ interest first in biotechnology and eventually in seed, thus changing their business models to meet farmer demand for crop pest management as technological opportunities changed.

2. On the other hand, the “life science industry” model suggested a decade ago has not become the dominant paradigm. This model stemmed from the likelihood that technologies underlying pharmaceutical discovery were the same as those underlying gene discovery for seeds. Differences in business models and types of customer, however, prevented firms from combining both pharmaceuticals and agricultural biotechnology. Of the current Big 6 companies, only one — Bayer — has pharmaceuticals as its primary product line.

Detail from the graphic, 'Formation of the 'Big 6' seed-biotech-crop companies'

Even when Bayer expanded into the seed/biotechnology industry in 2002 with its acquisition of Aventis Crop Science, Aventis pharmaceuticals eventually became a component of Sanofi-Aventis pharmaceuticals, not Bayer. Monsanto, which entered pharmaceuticals in the mid-1980s with its acquisition of Searle, was briefly held by Pharmacia before the agricultural enterprise was spun off as the “new Monsanto”; Pharmacia retained the pharmaceutical business segments. When Novartis’s chemical and seed businesses were merged with Zeneca’s agricultural chemical business in 2000 to form Syngenta, the pharmaceutical portion of Novartis remained intact as a separate large pharmaceutical company. BASF and DuPont ended their relatively smaller pharmaceutical investments after 2000 and 2001, respectively, and Dow had already sold its pharmaceutical subsidiary Marion Merrell Dow to Hoechst in 1996.

3. Agricultural chemicals have been an important part of product sales for all the Big 6 companies. However, positions in markets for non-agricultural chemicals have not remained constant, with some companies shedding these nonagricultural products. Monsanto divested this portion of its business to Solutia in 1997. When Ciba-Geigy and Sandoz merged to form Novartis in 1996, nonagricultural chemicals were spun off to Ciba Specialty Chemicals, which eventually was acquired by BASF. In response to antitrust considerations, Bayer sold selected insecticides and fungicides to BASF in 2003. DuPont sold its polymers business in the early 2000s.